Anatomy & Physiology I · Basic Chemistry for A&P
Water, Solutions, and Mixtures
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In 30 seconds
Water is the body's most abundant substance and the medium in which its chemistry happens. This section covers water's special properties, the difference between solutions, colloids, and suspensions, and how Concentration the amount of solute in a given amount of solution. is described. It builds directly on the polarity you met in the last section.
Why this matters
Roughly half to two-thirds of body weight is water. It transports nutrients and wastes, cushions organs, lubricates joints, and regulates temperature. Understanding solutions and concentration is essential for reading lab values, giving IV fluids, and mixing medications — everyday nursing tasks that depend on this chemistry.
The college version
Water's properties come from its polarity. Because water is polar (a partially negative oxygen and partially positive hydrogens), water molecules cling to one another and to other charged substances through hydrogen bonds. Four properties matter most:
- Solvency (the "universal Solvent the substance present in greatest amount that dissolves others (water, in the body)."). Water's polar ends surround and separate charged or polar solutes, dissolving them. Blood, urine, cytosol, and digestive juices are all water-based solutions. Nonpolar substances (fats) resist dissolving and must be carried by special transporters.
- High heat capacity. Water absorbs and releases a lot of heat with little temperature change, which buffers the body against sudden temperature swings and helps maintain homeostasis.
- High heat of vaporization. Evaporating water (sweat) carries away large amounts of heat, cooling the body efficiently.
- Cohesion and lubrication. Water molecules stick together (cohesion), producing surface tension and making water an excellent lubricant in serous and synovial fluids.
Water is also a reactant. In hydrolysis, water is added to split large molecules during digestion; in dehydration synthesis, water is removed to build them (covered in a later section). So water is not just the stage — it is sometimes an actor.
Mixtures: solutions, colloids, suspensions. A mixture blends substances physically without chemical bonding, so its components keep their properties and can be separated. Mixtures differ by particle size:
- Solutions have the smallest solutes (ions, small molecules like glucose), evenly scattered and never settling. Saline and blood plasma's dissolved salts are solutions.
- Colloids (emulsions) have larger particles that remain dispersed and can scatter light. Cytosol is a Colloid a mixture with larger particles that scatter light but stay dispersed (for example, cytosol). that can shift between fluid and gel states.
- Suspensions have the largest particles, which are visibly distributed but settle out when left standing. Whole blood is a Suspension a mixture with large particles that settle out if undisturbed (for example, blood cells in plasma). — spin it down and the red cells sink beneath the plasma.
Concentration. How much Solute a substance dissolved in a solvent. is present is described several ways: percent (grams per 100 mL), molarity (moles per liter), and, in clinical settings, units like milliequivalents per liter (mEq/L) for electrolytes and milligrams per deciliter (mg/dL) for glucose. Concentration matters because physiology depends on the right amount, not just presence — and because water moves toward higher solute concentration (osmosis), a theme in the cell unit.
How it works
Classifying a mixture:
- Do particles settle? Yes → suspension (blood cells in plasma).
- Do they stay dispersed but scatter light / can gel? → colloid (cytosol).
- Are solutes tiny, evenly spread, never settling? → Solution a homogeneous mixture with very small, evenly distributed solutes that do not settle. (saline).
Comparisons
| Mixture | Particle size | Settle out? | Example |
|---|---|---|---|
| Solution | Smallest | No | Saline, dissolved glucose |
| Colloid | Medium | No (dispersed) | Cytosol |
| Suspension | Largest | Yes | Blood cells in plasma |
Common confusions
- Solution vs suspension. Solutions never settle; suspensions do. Blood is a suspension because its cells settle when not moving.
- Solvent vs solute. Solvent dissolves (water); solute is dissolved (salt, glucose).
- Mixture vs compound. A mixture is physical (separable, components keep properties); a compound is chemically bonded.
- "Universal solvent" is not literal. Water dissolves many polar/charged substances but not nonpolar fats.
Memory aids
- "Solute is the smaller amount, Solvent is the greater" (both start with "sol," so anchor on amount).
- Suspension → things Suspended eventually Sink.
- Water cools by evaporation — "sweat = built-in AC."
Quick review
- Water's polarity makes it the body's solvent and gives it high heat capacity, cooling by evaporation, and cohesion/lubrication.
- Solutions (tiny solutes, never settle), colloids (dispersed, can gel), and suspensions (large particles, settle — like blood) differ by particle size.
- Concentration (percent, molarity, mEq/L, mg/dL) describes how much solute is present and drives water movement.

Eli explains
The same idea, in plain words
Explain it like I’m 10
Simple idea
Water is the body's main liquid, and it's amazing at mixing other things into itself so they can travel around.
Analogy
Think of water like a swimming pool full of helpers holding hands. When you toss in something like salt, the helpers surround each piece and pull it apart so it spreads out evenly — that's a solution. If you toss in something bigger, like blocks, they float around for a while but eventually sink to the bottom — that's a suspension, which is how blood cells behave in the liquid part of blood. In-between-sized bits that stay floating and can turn the pool slightly gel-like make a colloid.
What is actually happening
Water dissolves so many things because it's polar — its slightly-plus and slightly-minus ends grab onto other charged particles. That's why water is called the "universal solvent." Water also soaks up heat without getting hot fast, and cools you when it evaporates as sweat. The amount of a substance dissolved in water is its concentration, which nurses read on lab reports (like blood sugar) and control when giving IV fluids.
Where the analogy stops
Real water doesn't dissolve everything — oils and fats refuse to mix in, which is why salad dressing separates and why fats in blood need special carriers.
Key takeaway
IV fluids are solutions whose concentration is chosen deliberately — isotonic (0.9% saline), hypotonic, or hypertonic — because concentration drives water movement into or out of cells. Lab reports express results as concentrations (sodium in mEq/L, glucose in mg/dL), so reading them requires this vocabulary. Water's heat properties underlie why fever and heat loss behave as they do, and why sweating cools effectively.
Study tools & related lessonsYou’ll learn to · Key vocabulary · Related
You’ll learn to
- Describe water's key properties and their physiological roles.
- Distinguish solutions, colloids, and suspensions.
- Define solvent, solute, and concentration.
- Explain why water is called the "universal solvent."
Key vocabulary
- Solvent
- the substance present in greatest amount that dissolves others (water, in the body).
- Solute
- a substance dissolved in a solvent.
- Solution
- a homogeneous mixture with very small, evenly distributed solutes that do not settle.
- Colloid
- a mixture with larger particles that scatter light but stay dispersed (for example, cytosol).
- Suspension
- a mixture with large particles that settle out if undisturbed (for example, blood cells in plasma).
- Concentration
- the amount of solute in a given amount of solution.
Sources & references
- OpenStax, *Anatomy and Physiology 2e*, Chapter 2 (The Chemical Level of Organization): Inorganic Compounds — Water. https://openstax.org/details/books/anatomy-and-physiology-2e
- U.S. National Library of Medicine, MedlinePlus — Fluid and Electrolyte Balance. https://medlineplus.gov/fluidandelectrolytebalance.html
This lesson was adapted from the open educational references above; their licenses and attributions are preserved. See Copyright & Licensing.
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