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Chapter 11 of 31 · Organic Chemistry

Reactions of Alkyl Halides: Nucleophilic Substitutions and Eliminations

12 lessons in this chapter. Work through them in order, or jump to the one you need.

  1. The Discovery of Nucleophilic Substitution Reactions
  2. The SN2 Reaction
  3. Characteristics of the SN2 Reaction
  4. The SN1 Reaction
  5. Characteristics of the SN1 Reaction
  6. Biological Substitution Reactions
  7. Elimination Reactions: Zaitsev’s Rule
  8. The E2 Reaction and the Deuterium Isotope Effect
  9. The E2 Reaction and Cyclohexane Conformation
  10. The E1 and E1cB Reactions
  11. Biological Elimination Reactions
  12. A Summary of Reactivity: SN1, SN2, E1, E1cB, and E2